While it is helpful to occasionally use acetaminophen, aspirin, or NSAIDs (non steroidal anti-inflammatory drugs- ibuprofen), daily use of these drugs can cause damage.  These drugs are the leading cause of hospitalization for kidney failure, liver failure, and intestinal bleeding.  In the last few decades, they have been responsible for millions of hospital visits and thousands of deaths in the United States.  In 2006, Harvard Medical School released a report that every year 458 accidental deaths occur from painkillers.  They do not believe that this number will decrease anytime soon.  One of the major factors linked to the rise in accidental overdoses is known as “drug creep”-a dangerous influx of acetaminophen consumption due to the fact that numerous medications contain acetaminophen but treat different ailments.  Many people are not aware that their doctor prescribed medications often contain acetaminophen, and sometimes overdose when they take their painkiller along with a dose of an Over-The-Counter painkiller.  In the United States, acetaminophen is the number 1 reason for calls to Poison Control.  In the US and the UK, it is the leading cause of liver failure.