I purchased a 5oz tube of RTPR in St. Thomas while on a cruise and walking a lot. I have had osteoarthritis in feet, knee, hip and many other joints for some years. I have a drawer full of creams that didn't help. I used the RTPR while walking and experienced [quick] relief making the cruise more enjoyable. My wife had pain...tried it there and had [quick] relief. If this continues, I expect to use it for the rest of my life.