I have been suffering from osteoarthritis knee pain for a couple years to the point that I could not sleep at night because of the intense pain. I ordered some sample packs of RTPR to try the product. The first night I applied it, I slept through the night without any pain. I was so amazed with the results. It has been over a week since I have taken ibuprofen or aleve and I used to take them 4 at a time trying to get some relief. Thank you RTPR.