Since the 1890s, researchers have discovered the pain-reducing benefits of turmeric, through a substance it contains, which is called curcumin. The most prevailing aspect of curcumin is its ability to control inflammation. Recent studies have discovered that aspirin and ibuprofen are less effective than curcumin when it comes to relieving inflammation. The curcumin found in turmeric is one of the most effective natural treatments for rheumatoid arthritis, and studies show that curcumin naturally activates the opioid system in the brain. The curcumin in turmeric is so helpful in relieving inflammation, the U.S. Army Institute of Surgical Research suggests that it should be used to treat burns instead of the commonly used opioids. Since it does not have the negative side effects like painkillers do, turmeric/curcumin seems to be one of the safest and effective choices in fighting inflammation pain.