Toothpaste is one of the easiest things to use as a remedy for bruising. Toothpaste calms inflammation, and brings down the discoloration and swelling. To use toothpaste to help your bruises, mix toothpaste with lotion and apply the mixture to bruised skin before you go to bed. Cover the area with an ace bandage to prevent staining your bedding. When you wake up in the morning, wash the paste off of your skin. Repeat this process for the next two to three nights to ensure that you get maximum results.